Amidst all the key injuries the San Francisco 49ers have dealt with this season, there has been some hope that they would pull off a big trade to bring in a major reinforcement. They acquired defensive end Keion White from the New England Patriots this week, but he isn't the type of player who will likely make a significant impact.

ESPN's Ben Solak recently proposed several potential NFL trades ahead of the fast-approaching November 4 trade deadline. Among his suggestions, the San Francisco 49ers are identified as possible buyers—particularly in need of help along the defensive line after losing Nick...

The San Francisco 49ers fell to the Houston Texans on Sunday. How did it affect their standing heading into Week 9?

San Francisco 49ers fans voted on what they believe is the main reason for the team's winning record during the 2025 NFL season.

The NFL season continues when the Houston Texans host the San Francisco 49ers Sunday. Start time, how to watch, streaming and NFL TV schedule.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. The Texans are -151 money line favorites (risk $151 to win $100),

When the San Francisco 49ers finally picked up a first down Sunday against the Houston Texans they were already down by 16 points and there was less than a minute left in the first half.

George Kittle still believes the San Francisco 49ers have the "right guys" with the NFL trade deadline looming after the loss to the Houston Texans.