UPTON, NY -- By deciphering the near atomic-level structure of the catalytic domain of botulinum toxin type E -- one of seven neurotoxins that cause botulism, a disease that paralyzes victims by ...

Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

The toxin complex with its 14 components. The toxin itself is colored pink and sits at the top of the complex. The structure consists of tens of thousands of atoms, and here we only show the surface ...

Currently there's no treatment for botulism once the toxin gets into neurons. This novel treatment neutralized the toxin with a second, modified botulinum toxin that delivered a mini antibody into the ...

The Botox injections that smooth wrinkles rely on the ability of botulinum toxins from the bacterium Clostridium botulinum to block communication between cells. In the cosmetic treatment, these toxins ...

Two research groups have designed chimeric fusion proteins that constitute a new “trojan horse” approach to neutralize lethal botulinum toxins. Botulinum neurotoxins (BoNTs)—a family of bacterial ...

Botulinum toxin (BTX) has been used at Baylor’s Parkinson’s Disease Center and Movement Disorders Clinic (PDCMDC) in the treatment of dystonia and related disorders since 1983. Its safety and efficacy ...