Scientists have uncovered a surprising cause of age-related cognitive decline involving brain cells previously thought to be entirely beneficial. As these cells become dysfunctional, they can produce ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed ...

Neuroscientists have made a major advance in modeling the human brain in mice, offering a new way to study conditions like ...

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life. Scientists have reasoned that replacing the ...

Scientists at the University of California, San Diego School of Medicine just discovered a new brain phase. A single-cell study identified a new biological phase the brain may enter between 50 and 75.

When someone has a stroke—a leading worldwide cause of death and disability—time is of the essence. Almost nine out of 10 cases are ischemic strokes, caused by restricted blood flow in the brain, and ...

A single injection of a nanoparticle treatment engineered to encourage the generation of new brain cells was enough to reverse cognitive decline in an animal model of Alzheimer’s disease. Developed by ...

A PLOS Biology Perspective argues that immune and vascular cells, especially microglia, must be core components of neural ...

A new hypothesis proposes that von Economo neurons in the fronto-insular and anterior cingulate cortices act as biological ...

The tiny chips hitch a ride on immune cells to target inflammation in the brain. Scientists hope to kick off clinical trials within three years. From restoring movement and speech in people with ...