Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

Consider someone addicted to alcohol, drugs, or a behavior like gambling. Why do they continue, even when they say they want to stop? It's a question that highlights a fundamental disconnect: the gap ...

People with substance use disorder—whether addicted to alcohol, cocaine, heroin, or nicotine—share a strikingly similar pattern of abnormal brain connections, particularly within the brain’s reward ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

For decades, my colleagues and I advanced the premise that early substance use—nicotine, alcohol, or cannabis (or other addicting drugs)—interferes with critical maturation stages, particularly ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

Your endless scroll may be costing you more than just your time. New research shows it’s changing the way you think and make decisions. These days, almost everything is available in the form of quick, ...

A new study suggests that newer oral weight loss drugs may do more than suppress appetite, potentially altering brain circuits that control motivation and reward, impacting how one experiences ...

Consider someone addicted to alcohol, drugs, or a behaviour like gambling. Why do they continue, even when they say they want to stop? It’s a question that highlights a fundamental disconnect: the gap ...