Follow along with score and in-game updates as the Bills host the Chiefs on Sunday afternoon at Highmark Stadium.

Brandon Beane, general manager of then Buffalo Bills, heads off the field at the end of practice at the Buffalo Bills training camp at St. John Fisher University in Pittsford on July 24, 2025. / Tina MacIntyre-Yee/Democrat and Chronicle / USA TODAY NETWORK via Imagn Images

The Kansas City Chiefs were down 21-13 to the Buffalo Bills, and Travis Kelce, the quarterback, took a heavy hit in the end zone and appeared to have some chest injury. This happened during the halftime on Sunday in Buffalo.

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the Buffalo Bills and Miami Dolphins.

Sean McDermott and the Buffalo Bills pulled off a big win on Sunday, taking down the Kansas City Chiefs, 28-21. Unfortunately for Buffalo, the victory came at a substantial cost, with defensive tackle Miachael Hoecht suffering a non-contact foot injury during the game.

Kansas City is a two-point favorite in the latest Chiefs vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 52.5. The Chiefs are -131 money line favorites (risk $131 to win $100),

Kansas City will still face an uphill battle to overcome Buffalo's lead. Bills quarterback Josh Allen is putting on a dominant performance, and Chiefs defensive coordinator Steve Spagnuolo must find a way to put the clamps on the reigning MVP if Kansas City intends to win its sixth game of the season.

It's the regular season, and the game is at Highmark Stadium, so the Buffalo Bills must have the edge. On the other hand, it's the Kansas City Chiefs and in big games they seem to always find a way to break the hearts of Bills Mafia.