Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...
A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to pause ...
LMU scientists have shown that a fundamental process of life works differently than previously assumed. The basic process of life, known as transcription, is the process by which the genetic ...
RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...
As imaging tools continue to get more sophisticated, researchers have been able to actually watch biological processes as they are happening in live cells. Scientists have now visualized loops of DNA ...
When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...
A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...
A recent study in Nature Communications examined how RNA polymerase I (Pol I) responds to abasic (Ap) site formation—the most common type of DNA damage. The researchers found that Pol I helps maintain ...
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