Medically reviewed by Scott Zashin, MD Key Takeaways People taking methotrexate should avoid alcohol because it can increase the risk of liver damage.Some NSAIDs like aspirin should not be taken with ...

“The studies continue to demonstrate a role for the intestinal microbiome in methotrexate responsiveness,” Kristi Kuhn, MD, PhD, a professor of medicine at the University of Colorado Anschutz Medical ...