Over the last decade, experiments addressing thyroid hormone's role in the retina have generated a sizeable body of data. They have also inspired many more questions that will no doubt be tested in ...

Thyroid hormones influence gene expression in virtually all vertebrate tissues. Precise regulation of the active endogenous ligand, 3,5,3'-triiodothyronine (T 3), is achieved by the sequential removal ...

The role of this enzyme has been studied in a D3 knockout (D3KO) mouse model. The D3KO mice were carefully engineered to lack all D3 activity without noticeably affecting transcripts of another gene ...

Molecular Tumor Board–Assisted Care in an Advanced Cancer Population: Results of a Phase II Clinical Trial The development of the selective RET inhibitors selpercatinib and pralsetinib has ...

In men with hypopituitarism, treatment with growth hormone therapy is associated with changes in circulating thyroid hormone levels and deiodinase enzyme activity, although the mechanism behind the ...

New Rochelle, NY, December 19, 2017--Researchers now have a better understanding of the role that thyroid hormones, the tissues that produce them, and the biochemical pathways on which they act have ...

Show More 1 Department of Medicine, Division of Endocrinology, Memorial Sloan Kettering Cancer Center, New York, NY The development of the selective RET inhibitors selpercatinib and pralsetinib has ...