Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...
As DNA strands ravel and unravel in an intricate dance, one notable event takes center stage: replication. This process is essential to life, but the finer details of its orchestrated steps are still ...
Researchers uncover a crucial hidden function of the protein RPA, revealing how its failure to activate telomerase leads to ...
Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to ...
A new study led by researchers at the University of Pittsburgh (Pitt) and UPMC Hillman Cancer Center has shown that an enzyme called PARP1 is involved in the repair of telomeres, the lengths of DNA ...
There’s a new argument against “junk DNA.” In this microscope image, the ends of chromosomes are protected by specific DNA sequences called telomeres, visualized here in red. Credit: National ...
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of ...