The rapid increase in type 2 diabetes (T2D) incidence results from a combination of lifestyle factors and genetics. Recent genome-wide association studies have identified close to 50 loci associated ...
Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair
Rapid plasma membrane resealing is essential for cellular survival. Earlier studies showed that plasma membrane repair requires Ca2+-dependent exocytosis of lysosomes and a rapid form of endocytosis ...
A study has identified a key activation mechanism that leads to vesicle fusion to the plasma membrane, a part of exocytosis. Every time a hormone is released from a cell, every time a neurotransmitter ...
An international group of researchers led by Pompeu Fabra University has discovered the nanomachine that controls constitutive exocytosis: the uninterrupted delivery of spherical molecular packages to ...
Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...
The fight against cancer often begins with uncovering hidden players, and this study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in cancer ...
There are few scientific methods more elegantly simple than "just sprinkle it on top." Researchers at Tohoku University and Nagoya University developed a fluorescent probe that can quickly show ...
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