Morning Overview on MSN
Cancer’s most notorious protein MYC quietly repairs the DNA damage chemo inflicts — block that trick and treatment could hit tumor cells far harder
Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be lethal. But in tumors that overexpress the oncoprotein MYC, and that ...
Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...
Morning Overview on MSN
Cancer’s most notorious protein MYC quietly repairs tumor DNA damage behind the scenes — scientists say blocking the trick could multiply what chemo already does
Chemotherapy drugs are designed to shatter tumor DNA so thoroughly that cancer cells cannot survive. But one of the most common cancer-driving proteins, MYC, appears to run a quiet rescue operation in ...
Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...
Efforts to develop effective therapies for MYC-amplified Group 3 medulloblastoma (G3-MB) are hindered by an incomplete understanding of how MYC expression is controlled in these tumors. MYC, an ...
A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional ...
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