Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein. CTCF is a critical protein known to play various roles in key biological ...

Transcription is the first step of gene expression, where a DNA sequence is copied into messenger RNA. In eukaryotes, transcription initiation starts with the assembly of the transcription ...

St. Jude Children’s Research Hospital scientists have revealed a previously unknown role for CTCF, a pivotal transcription regulator linked to cancer. CTCF is known by biologists for being a master ...

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC. Scientists at St. Jude Children's Research Hospital have found direct ...

Transcription factors are an essential part of gene expression. Some of these proteins are known as master regulators, and they can have an impact on many different biochemical pathways and processes ...

(Memphis, Tenn.—January 25, 2023) CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children’s Research Hospital used a ...