A recent study posted on the bioRxiv* preprint server explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for developing broad-range pan-coronavirus vaccines. Study: The ...

In physiological conditions, most proteins are coated with complex sugars via N- and O-glycosylation, which are mobile and dynamic, influencing how proteins interact with other molecules. The dynamic ...

A type of glycan called “N-glycan” is usually extended by the actions of several enzymes (glycosyltransferases). The terminal sugar “sialic acid” increases protein stability in blood. Once B4GALNT3 ...

In the fight against infectious diseases, the most daunting foes include viruses that use glycans to fend off antibodies. These glycans form on the outermost spike proteins of HIV and many other ...

Monoclonal antibodies (mAbs) dominate the biotherapeutic market, with numerous products designed to provide treatments for cancer or immune diseases such as Crohn’s disease, rheumatoid arthritis, and ...

"The exceptionally high level of G0 glycans reached through our glycoengineering work with C1 was a very important interim goal in our ongoing C1 research and development program with Dyadic where we ...

Sepsis—an extreme inflammatory response in the bloodstream caused by a serious infection—could be responsible for as many as 11 million deaths worldwide per year, according to a 2020 report from the ...

All bee larvae eat royal jelly when they're new, but only future queens continue to eat it. To figure out why, researchers are taking a close look at the molecular ingredients of the fancy fare.