Vascular endothelial cells (ECs) sense and respond to hemodynamic forces such as pulsatile shear stress (PS) and oscillatory shear stress (OS). Among the metabolic pathways, glycolysis is ...
Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice ...
Thus, our studies revealed regulatory mechanisms of glycolysis-driven cellular senescence by AUF1-mediated decay of PGAM1 and PDP2 mRNAs.” "Thus, our studies revealed regulatory mechanisms of ...
Researchers at the University of Tokyo report they have uncovered an enzyme called Akt2 that when activated, plays a vital role in initiating glycolysis which involves breaking down glucose to produce ...
The researchers say it was taught in biochemistry class for many decades that glycolysis occurred uniformly in the cytosol, or the fluid matrix of the cell. But when the Johns Hopkins team examined ...
Axon damage is an early sign of neurodegenerative diseases like, ALS, Alzheimer's, Huntington's and Parkinson's. Researchers found that nicotinamide nucleotide adenylyl transferase 2, or NMNAT2, can ...