Interferon lambda concentrations in nasal lining fluid fell in or above the predicted therapeutic range with a nasally ...

A schematic diagram illustrates a proposed mechanism of interferon-γ (IFN-γ)-induced downregulation of tricellulin in salivary epithelial cells. IFN-γ leads to the phosphorylation of signal transducer ...

Molecular Biology of Anaplastic Lymphoma Kinase–Positive Anaplastic Large-Cell Lymphoma PURPOSE: The toxicity associated with adjuvant high-dose interferon-alfa-2b therapy (HDI) for high-risk melanoma ...

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help ...

Irish scientists led by a group from Trinity College Dublin have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an ...

Nadofaragene firadenovec is the first and only non-replicating gene therapy administered intravesically, and it is already approved and launched in the US This represents the first filing ...

PURPOSE: The toxicity associated with adjuvant high-dose interferon-alfa-2b therapy (HDI) for high-risk melanoma can lead to premature discontinuation. It is important to understand the expected ...