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Behar et al 1 and Wang et al 2 first reported that intrathecal and epidural opioids were effective for acute and severe pain in humans. Despite the early reports regarding the analgesic efficacy of ...

The FDA has relaxed a clinical hold on clinical trials of Novartis' intrathecal formulation of spinal muscular atrophy (SMA) gene therapy Zolgensma, allowing a new phase 3 trial to get underway.

Credit: FDA. The FDA has received reports of tranexamic acid injection being erroneously administered intrathecally in the perioperative setting instead of the intended intrathecal anesthetic (eg, ...