Nature

A comparison of molecular and cytogenetic techniques for the diagnosis of pregnancy loss

Purpose: To evaluate the sensitivity, specificity, advantages, and limitations of multiplex ligation-dependent probe amplification compared with conventional karyotype analysis in the investigation of ...
Nature

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas

Expression of the DNA repair protein O6-alkylguanine-DNA-alkyltransferase (AGT), encoded by the O6-methylguanine (O6-mG) -DNA-methyltransferase (MGMT) DNA repair gene, results in resistance to ...
Science Daily

Cheap, simple, noninvasive blood test may replace invasive diagnostic techniques in early pregnancy

Researchers in the Netherlands believe they are on the verge of developing a simple, prenatal blood test that would be able to detect accurately chromosomal abnormalities in the developing fetus. At ...
GEN

Existing Technique Can Detect Fetal Genetic Abnormalities in Maternal Blood

Team found that MLPA assay can identify fetal DNA without invasive sampling. Netherlands-based researchers suggest that a technique currently used to detect fetal chromosomal abnormalities in maternal ...
News24

MLPA testing

have you heard about mlpa testing to check for dna malfunctions and to pick up syndromes. do you know of any good geenticist in the johannesburg area Answer::MLPA is a recognised test in genetics.
ascopubs.org

Screening for genomic rearrangements in BRCA1 and BRCA2 genes in 16 Peruvian breast cancer families by Multiplex Ligation-dependent Probe Amplification (MLPA).

Potential germline relevance of tumor testing and the need for genetic referral. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not include a full text ...