New research shows lung injury and dysregulated macrophages create an environment that supports tuberculosis growth, offering ...
Macrophage activation syndrome (MAS) is a rare but serious complication that can happen in people with Still's disease. Still's disease is a type of inflammatory condition that causes daily fevers, ...
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Cholesterol biosynthetic intermediates, such as lanosterol and desmosterol, are emergent immune regulators of macrophages in response to inflammatory stimuli or lipid overloading, respectively.
Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.
Macrophages are highly specialized cells of the immune system that help the body detect and fight deadly pathogens. In particular, M1-like macrophages detect and destroy tumor cells, and release ...
Background: Porcine genome editing has revolutionized xenotransplantation, recently enabling the first pig-to-human heart xenotransplants. However, the xeno-immune response in heart xenografts remains ...
This diagram illustrates the role of macrophage ATF6 in orthodontic tooth movement. When corticotomy is applied, monocytes are recruited to the bone, where they differentiate into pro-inflammatory ...
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