Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Once engineered, the mast cells were loaded with oncolytic viruses, which are designed to infect and kill cancer cells while ...

Mast cell platform can expand to carry other payloads, such as molecules, viruses, proteins and drug-loaded nanoparticles.

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Researchers have engineered an experimental vaccine that can provide year-long protection against anaphylaxis in mice. This severe, systemic allergic reaction can be deadly. The vaccine, called IgE-K, ...

Among adults with evidence of systemic mast cell activation, bone marrow samples allowed for detection of 13 additional ...

Chinese scientists have ingeniously transformed allergy-inducing mast cells into a potent weapon against cancer, using them ...

In a recent study published in Nature, researchers used a mouse model to show that mast cells and immunoglobulin E (IgE) are the key orchestrators of antigen-specific avoidance, a behavioral ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Researchers led by the Institut Pasteur, Université Paris, have developed a vaccine that elicits anti-Immunoglobulin E antibodies in humanized mice, protects against Immunoglobulin E-mediated ...

Mast cell platform can expand to carry other payloads, such as molecules, viruses, proteins and drug-loaded nanoparticles.