Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, No. 21 (May 21, 2013), pp. 8561-8566 (6 pages) Myosin filaments of muscle are regulated either by ...

Smooth muscle cells use an actin-myosin II-based contractile apparatus to produce force for a variety of physiological functions, including blood pressure regulation and gut peristalsis. The ...

The sarcomere of muscle is composed of tens of thousands of myosin motors that self-assemble into thick filaments and interact with surrounding actin-based thin filaments in a dense, near-crystalline ...

Recent X-ray diffraction studies on actively contracting fibres from skeletal muscle showed that the number of myosin motors available to interact with actin-containing thin filaments is controlled by ...

At the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. New electron cryomicroscopy images with unprecedented resolution taken by researchers at Osaka ...

Researchers have described, for the first time, the ordered arrangement of myosin-II filaments in actin cables of non-muscle cells. Researchers from the Mechanobiology Institute, Singapore (MBI) at ...

In a decades-long effort, researchers have discovered how to tweak the molecular pathways that turn heart muscle motors up or ...

Dr. Colleen Kelly, a renowned postdoctoral researcher from the Previs Lab at the University of Vermont, will discuss cellular and molecular methods used to study myosin. Our expert speaker will ...

Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

The Moore lab investigates how proteins build contractile systems that power cells and whole organisms. Collaboratively, we connect molecular mechanisms to tissue-level performance using ...