Myosin-V processively walks on actin filaments in a hand-over-hand fashion. The identical structures of the heads predict a symmetric hand-over-hand mechanism where regular, unidirectional rotation ...

Certain smooth muscles are able to reduce energy consumption greatly when holding without shortening. For instance, this is the case with muscles surrounding blood vessels used for regulating blood ...

Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 81, No. 4, [Part 1: Biological Sciences] (Feb. 15, 1984), pp. 1003-1007 (5 pages) Methods have been devised for ...

In a decades-long effort, researchers have discovered how to tweak the molecular pathways that turn heart muscle motors up or ...