The Bears' defense will have their hands full against Brock Purdy and the 49ers, who've totaled 85 points over the last two weeks. All-world running back Christian McCaffrey already has over 1,000 rushing yards (1,039) and is tracking to surpass 1,000 receiving yards, too. He enters Week 17 with 849 yards and seven touchdowns as a receiver.

Still alive to win their sixth straight AFC East crown, the Bills were guaranteed at least their playoff shot with the Colts' loss