Coiled tertiary structure that forms when strain is placed on a DNA helix by overwinding or underwinding of the helix. An overwound DNA exhibits positive supercoiling; an underwound DNA exhibits ...
TOP2A relieves negative supercoiling at gene promoters, resulting thus in an increase in the number of twists of the DNA strands. This is an obstacle to the continuous opening of the helix that ...
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...
When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...
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