Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

Excessive reactive nitrogen species (RNS) and reactive oxygen species (ROS), such as H 2 O 2 (hydrogen peroxide), HO − (hydroxyl radical), HOO − (hidroperoxil), NO − (nitric oxide radical), NO 2− ...

Researchers aren’t sure exactly what causes Alzheimer’s, but they do know that it’s linked to a buildup of protein clumps and knotted clusters of molecules in the brain. Called beta-amyloid plaques ...

Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role in the development of non-communicable diseases (NCDs). These diseases, ...

Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

You may have heard about oxidative stress on social media. A TikTok search offers dozens of videos that claim to break down the complex chemical process and, in some instances, offer up “treatments” ...

People with type 2 diabetes are more likely to develop heart failure, but the reasons are not fully explained by cholesterol, blood pressure and blocked arteries alone. A new study adds another piece ...

Researchers have discovered how the tau protein turns from a normal to a disease state in Alzheimer's disease (AD) and have shown how the discovery could potentially deliver a therapeutic target.

Oxidative stress occurs when there is an imbalance between the production of free radicals and the body’s ability to counteract them. When you purchase through links on our site, we may earn an ...

It is well understood that the neurodegenerative disorder Huntington’s disease is caused by an N-terminal polyQ-expansion (>35) in the Huntingtin (HTT) gene. This mutation leads to axonal degeneration ...