MRD detection by PCR analysis of rearranged Ig/TCR genes is however a complex process, involving many steps (Figure 1). Identification of pitfalls in this process is of importance in order to ensure ...

PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected lymphoproliferations has largely been standardized and has consequently become technically feasible in a routine ...

Multiplex PCR is a difficult technique that allows amplification of two or more products in parallel in a single reaction tube. This technology was first described by Chamberlain et al., in 1988, and ...

February 18, 2011 — The US Centers for Disease Control (CDC) has issued a statement on best practices for the use of polymerase chain reaction (PCR) to diagnose pertussis, as posted online and ...

UgenTec, the Belgian bioinformatics company that is developing universal & intelligent PCR analysis software, has received its ISO 13485 certification. Quickly following the new certification, UgenTec ...

Molecular laboratories face an increasingly high workload and regulatory burden, making manual test analysis insufficient to keep up with demands. Moreover, test interpretation and reporting require ...

In the six decades since Watson and Crick identified the double helical structure of DNA, a series of elegant and powerful experiments has established the broad outlines of how genetic information is ...

The third session of the ‘IAEA and WPRO Webinar Series to Support the COVID-19 Testing Laboratories in the Asia and the Pacific Region’, provides information on the principles of quality assurance and ...

Two widely used rapid screening tests for COVID-19, which check for SARS-CoV-2 antigens, missed a significant fraction of infected individuals when used in a real-world setting, researchers reported.

The development of the polymerase chain reaction (PCR) in 1983 by Kary Mullis and coworkers revolutionized molecular biology, allowing scientists to amplify DNA sequences for various applications. 1 ...