Penicillinase is an enzyme that acts on the β-lactam ring of penicillin to convert penicillin into penicillic acid, which has no antibacterial activity. A variety of penicillin-resistant bacteria can ...

WITH the long-acting depot penicillins in general use today, prolonged blood levels also prolong the sensitivity reactions when they occur. The use of ACTH and cortisone as anti-inflammatory agents to ...

WHILE studying the kinetics of penicillinase inactivation of various penicillins, it became evident that a penicillinase-susceptible penicillin, such as benzyl-penicillin, behaved differently from ...

WHEN the results of a gram stain or culture of material in a serious case of staphylococcal infection become known, and before the susceptibility of the organism has been determined, the physician is ...