Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

Researchers have discovered how the tau protein turns from a normal to a disease state in Alzheimer's disease (AD) and have shown how the discovery could potentially deliver a therapeutic target.

The protein LC3 is then recruited to help break down ... This enrichment subsequently recruits the Rubicon-containing PI3-kinase complex required to start the enzymatic cascade that triggers LAP. Thus ...

A novel substance disrupts stress management in cancer cells and offers new therapeutic approaches to treating tumours.