The researchers discovered that the lipid phosphatidylinositol-4-phosphate (PI4P)—usually scarce in the ER—acts as a ...

Protein trafficking is a fundamental cellular process that ensures efficient sorting, modification, and delivery of proteins to their correct subcellular destinations. At its core, this process ...

Just like in yeast and animal cells, vacuoles in plants are responsible for breaking down unwanted cellular components. At ...

Using state-of-the-art cell imaging and genome editing technology, scientists have begun to unravel how this collection of proteins performs its essential service. The discovery could eventually help ...

Endosomal trafficking and protein sorting constitute fundamental processes that govern the intracellular localisation and recycling of membrane proteins in eukaryotic cells. Endosomes act as central ...

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones - or chemical messengers - bind to cell membrane receptors to fine tune how ...

For Amy Engevik, an epithelial cell biologist at the Medical University of South Carolina who studies cell function in the gastrointestinal tract, protein location matters more than abundance. She ...

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

In a pioneering discovery, researchers at UNIST have captured, for the first time, the elusive intermediate stages involved in the pairing of cell membrane proteins. Contrary to long-held beliefs that ...

Cancer-associated fibroblasts play key roles in the pancreatic tumor microenvironment, but their targeting has yet been ...

Upon perception of blast pathogen effectors by the NLR, PIBP4 and OsRab5a-mediated trafficking vesicles likely promote the localization of part of PigmR to microdomains where PigmR interacts with and ...