Here is where the San Francisco 49ers sit in the 2025 NFL Week 10 power rankings after their win over the New York Giants.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-20 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

These coaches are friends who joined the division at the same time, are considered offensive geniuses and have had successful tenures as coaches of their respective teams. When they meet on NFL Thursday Night Football, McVay’s Rams are in much better shape when it comes to team health and availability.

The Rams and 49ers announced which players won't suit up in tonight's game, including Rob Havenstein, Tyler Higbee and Brock Purdy.

Thursday Night Football for Week 5 renews an NFC West rivalry when the San Francisco 49ers head south to take on the Los Angeles Rams. These teams have dominated the division since 2017, winning seven of the last eight division titles combined. The 2017 season was also the first of Kyle Shanahan's and Sean McVay's tenures.

Los Angeles Rams wide receiver Puka Nacua was forced to leave the game against the New Orleans Saints due to a chest injury.

The San Francisco 49ers visit the LA Rams in a marquee divisional matchup on Thursday Night Football at SoFi Stadium in Inglewood, California.

The San Francisco 49ers stayed atop the NFC West with a miracle win over the Los Angeles Rams in Week 5. Here are the highlights.

Matthew Stafford spoke candidly after drawing telling remarks from one of his Los Angeles Rams and defeating the New Orleans Saints.

It can’t continue like this,” head coach Sean McVay said after the Rams’ 34-10 win over the New Orleans Saints. Kicker Josh Karty missed two kicks Sunday.

Bijan Robinson and the Atlanta Falcons will face Drake Maye and the New England Patriots in Week 9 of the NFL season on Sunday.