Every day our kidneys tackle the daunting task of continuously cleaning our blood to prevent waste, salt and excess fluid from building up inside our bodies. To achieve this, the kidneys' ...

Extract: This report concerns two patients with primary renal tubular acidosis (RTA) in whom the abnormality in hydrogen excretion was shown to result from inappropriate urinary loss of bicarbonate ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

The calcium-sensing receptor (CSR) is a G-protein receptor that plays a critical role in calcium regulation. In the kidney, the CSR regulates calcium reabsorption in the thick ascending limb, where ...

This is a preview. Log in through your library . Abstract FK506 has been used as the primary immunosuppressive agent administered after a variety of organ transplants, with less reported ...

The USC Stem Cell laboratory of Andy McMahon has identified a type of injured cell that might contribute to the transition from an acute kidney injury to chronic kidney disease, as described in a new ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 19 (Oct., 1990), pp. 7457-7461 (5 pages) Rat carbonic anhydrase (CA) IV was purified by affinity ...