G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

An internationally recognized leader in molecular pharmacology and neurobiology, Dr. Bohn recently joined USF Health. She is ...

Researchers at the Kanazawa University Graduate School of Medical Sciences report in PLOS Pathogens a novel role for the ...

Researchers have used large-scale virtual compound libraries, in silico screening and computer simulations to identify small ...

Researchers at Karolinska Institutet have identified small molecules capable of influencing a hard-to-target receptor family ...

"To provide direct evidence for binding of the molecule at different pockets of the receptor, we have developed a new assay, which enables us to measure the binding specifically at the extracellular ...

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of ...