RPE cells displaying cobblestone morphology. Cells were immunolabeled with tight-junction ZO-1 marker (shown in green) and co-stained with nuclei marker, Hoechst (shown in blue). Image Credit: ...

X-linked retinoschisis gene replacement therapy, aiming to improve retinal architecture and visual function in young male ...

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception. The scientists from the National Eye Institute (NEI) ...

Scientists have developed a new, experimental human cell line from retinal pigment epithelial cells. Called ABC, these cells so closely resemble and retain the properties of native retinal pigment ...

This story is part of a series on the current progression in Regenerative Medicine. This piece is part of a series dedicated to the eye and improvements in restoring vision. In 1999, I defined ...

RPE from mice without Serpin1 accumulate more lipids than wild-type mice. Super-resolution confocal microscopy of RPE tissue from wild-type (upper) and Serpin1-null (lower) mice. Detailed images on ...

A clinical trial is investigating whether a stem cell-derived patch can replace disease-damaged cells and restore vision. Age-related macular degeneration is a steadily worsening eye disease and the ...

Multimodal imaging, including OCT and FAF, is crucial for differentiating between AMD and IRDs, enabling precise diagnosis.

Opus Genetics (Nasdaq: IRD) (“Opus Genetics” or the “Company”), a clinical-stage biopharmaceutical company developing gene therapies to restore vision and prevent blindness in patients with inherited ...

Vision accounts for more than 80% of the information humans obtain from the outside world. The ability of the eyeballs to capture and process visual information sent onward to the brain relies ...