Compound libraries form a foundational element of modern drug discovery—the process of identifying new chemical or biological compounds that can become safe and effective medicines. Compound libraries ...

In drug discovery, various methods of lead generation exist that give researchers a starting point to develop drugs further and make them as efficacious as possible. High-throughput screening is a ...

The size of compound libraries amenable to standard virtual ligand screening (VLS) approaches is limited by the time and cost involved in screening. To keep pace with the increasing size of virtual ...

The identification of compounds that could be promising candidates for drug development has become easier following research by the Walter and Eliza Hall Institute's medicinal chemistry group. Dr ...

Proteins with desirable properties are often identified by screening libraries of related gene sequences. Successful applications include antibody engineering, vaccine development, and biocatalyst ...

All compound libraries have been reformatted for high-throughput screens in both 96- and 384-well plate format. All screening compounds are commercially available and can be individually re-ordered ...

Metrion Biosciences Limited (“Metrion”), the specialist ion channel and cardiac safety screening contract research organization (CRO) and drug discovery company, and Enamine Ltd (“Enamine”), the ...

Generation of fragment screening libraries could enhance the analysis and application of natural products for medicinal chemistry and drug discovery, according to researchers. In a new article, ...