Study finds widely prescribed opioid painkiller tramadol shows limited effectiveness for chronic pain while increasing risk ...

A major medical review finds tramadol provides only modest chronic pain relief while significantly increasing the risk of ...

Many surgeons recommend giving up smoking, alcohol, or drugs before surgery, but researchers have found this may also ...

A new study, published in the Annals of Emergency Medicine, examined opioid prescription patterns in emergency and non-emergency settings. Researchers analyzed 5.2 million prescriptions for opioids ...

Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

The Assessment for the Appropriate Use of Opioids in Long Term Care demonstrated evidence of validity but still requires future testing with a larger, heterogeneous sample to further corroborate its ...

Acupuncture significantly lowers methadone doses for people undergoing treatment for opioid use disorder, while restoring antiviral immune responses and rebalancing gut microbiota and metabolism. This ...

About 1 in 10 veterans with early-stage cancer developed new persistent opioid use after curative‐intent surgery, though less than 1% were diagnosed with opioid use disorder. “Although a cancer ...

Young adults between ages 13 and 30 who fill an opioid prescription before or after having their wisdom teeth are 2.7 times more likely to demonstrate continued opioid use, according to a study ...

Opioid medications will be required to have their labeling updated to highlight the safety risks of long-term use, the FDA announced on Thursday. The agency is requiring opioid manufacturers to add to ...