The chaperone Hsc70 (green) helps keep SNAP-25 in the proper shape so that it can help form the SNARE complex, enabling neurotransmission. AMHERST, Mass. – A team of researchers from the University of ...
The peptide commonly referred to as SNAP-8 (acetyl octapeptide-3) is a synthetic fragment derivative of SNAP-25, engineered ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When ...
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