The genome contains all of the instructions a cell needs to build an organism. In coding regions of the genome, genes are transcribed into a molecule called mRNA, which is processed and then ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

(Nanowerk News) A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The ...

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study. The findings advance ...

This is a preview. Log in through your library . Abstract We have previously observed (Klein, R. R., and J. E. Mullet, 1986, J. Biol. Chem. 261:11138-11145) that translation of two 65-70-kD ...

When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...

Proteins, we hear you loud and clear. A group of researchers from Massachusetts Institute of Technology (MIT) devised an artificial-intelligence (AI)-based approach to translate each of the 20 amino ...