The recently published recommendations of the European Commission Joint Research Centre (JRC) shine a spotlight on the versatility and scientific benefits of universal antibody libraries in ...
When a pathogen infects a healthy host, the host’s immune system responds to fight it off and maintain health. The host produces antibodies that recognize the antigens present on the surface of the ...
Co announces that they have licensed their antibody phage display libraries to Cambridge Antibody Technology, a wholly-owned subsidiary of AstraZeneca (AZN), for the discovery of therapeutic ...
Mapping the individual amino acids where antibodies bind (epitopes) to target viral proteins (antigens) is crucial to predicting how target proteins may evolve to escape antibody binding, improve ...
Clinical drug candidates must have not only appropriate affinity and target specificity, but also optimal biophysical properties. Using nuclease-directed integration, we constructed large mammalian ...
A single-chain Fv antibody fragment specific for the tumor-associated Ep-CAM molecule was isolated from a semisynthetic phage display library and converted into an intact, fully human IgG1 monoclonal ...
Reviewed by Michael Greenwood, M.Sc. In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug ...
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon ...
WILMINGTON, Mass. & SAN FRANCISCO--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL) today announced the Company will provide clients exclusive access to the new Cosmic ...
Membrane proteins are important therapeutic targets as they transduce signals into cells, transport molecules, bind to surfaces, and catalyze reactions. However, researchers face challenges when ...
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