How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Messenger RNA (mRNA) technology came of age during COVID-19 with several vaccines and therapeutics coming to market. However, since the height of the pandemic, the flow of new mRNA-based products has ...

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the ...

Neurodegenerative diseases are commonly adult-onset conditions characterized by degeneration of specific neuronal populations. Familial forms are caused by mutations in single genes, but most patients ...

The discovery of chemical modifications to overcome mRNA’s instability and immunotoxicity have enabled mRNA therapeutics to evolve dramatically, reaching clinical trials and the forefront of modern ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the ...

(A) Bar plot of IARS2 transcription level in different cancer types. (B) TCGA and GTEx databases showed IARS2 transcription level was higher in tumor tissue compared with normal pancreas tissue. (C) ...