Ohio had two $100,000 Powerball winners in Wednesday night's drawing. The tickets were sold at a convenience store in Willoughby, Ohio and a Kroger store in Sylvania, Ohio. Ahead of Wednesday's drawing, the grand prize was at an estimated $643 million, which was already the 13th largest prize in the history of Powerball.

The Powerball jackpot has climbed to $643 million, with the next drawing set for Wednesday night.

A $2 million winning ticket was sold in Tennessee for the Wednesday drawing, matching five numbers plus the Power Play.