Gut

Impaired glucose metabolism in irritable bowel syndrome: personalised low-glycaemic diet as potential therapeutic target

We read with great interest the recent study by Gilliam-Vigh et al demonstrating significant transcriptomic alterations in ...
Gut

Rise of precision medicine: can it deliver on its promise in IBD?

The clinical and molecular heterogeneity of IBD—both between patients and within the same individual over time—continues to ...
gut.bmj

Response to ‘Biliary sludge and microlithiasis: are we covering the full spectrum of lithogenic biliary disorders?’

Correspondence to Professor Julia Mayerle, Department of Medicine II, LMU University Hospital, Munich, Bavaria, Germany; julia.mayerle{at}med.uni-muenchen.de If you wish to reuse any or all of this ...
Gut

FODMAPs and functional dyspepsia: emerging evidence but unanswered questions

Functional dyspepsia (FD) is a common disorder of gut-brain interaction (DGBI) characterised by symptoms of epigastric pain ...
gut.bmj

Galectin-4 drives anti-PD-L1/BVZ resistance by regulating metabolic adaptation and tumour-associated neutrophils in hepatocellular carcinoma

Background The combination of atezolizumab and bevacizumab (ATZ/BVZ) therapy has significantly advanced therapeutic approaches for hepatocellular carcinoma (HCC). However, less than 30% of patients ...
gut.bmj

Vonoprazan-based versus proton pump inhibitor-based therapy in Helicobacter pylori eradication: an updated systematic review and meta-analysis of randomised trials

We read the Maastricht VI/Florence consensus report published in GUT with great interest.1 The report suggested that vonoprazan-based therapy is superior, or not inferior, to conventional proton pump ...
gut.bmj

Enhancing non-invasive early detection of gastric cancer: a critical reflection on exosome ncRNA and machine learning

We have carefully reviewed the article titled ‘Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study’ by ...
gut.bmj

Geographical variability and environmental risk factors in inflammatory bowel disease

1 Department of Medicine and Therapeutics, Institute of Digestive Disease, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong 2 Department of Internal ...
gut.bmj

Effect of gastric acid suppressants on human gastric motility

Gastroenterology Section, Department of Medicine and Nuclear Medicine Section, Department of Diagnostic Imaging, Temple University School of Medicine, Philadelphia, Pennsylvania, USA Dr H P Parkman, ...
gut.bmj

A new variable stiffness colonoscope makes colonoscopy easier: a randomised controlled trial

BACKGROUND Colonoscopy remains technically difficult in 10–20% of procedures due to variable colonic anatomy and fixation. The ability to vary endoscope shaft flexibility may help insertion to the ...
gut.bmj

Race-dependent association of sulfidogenic bacteria with colorectal cancer

3 Center for Clinical and Translational Science, University of Illinois at Chicago, Chicago, Illinois, USA 9 Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, ...
gut.bmj

The influence of a preserved colon on the absorption of medium chain fat in patients with small bowel resection

Background—Medium chain C8–C10 triglycerides (MCTs) improve fat absorption in short bowel patients. Effects on overall energy absorption remain unknown. Aims—To determine whether MCTs and medium chain ...