NEW MADRID, Mo. (WSIL) -- One person was seriously injured after a crash along I-55 in New Madrid County on Tuesday evening.

Today, prepare for gusty winds that will make it feel cold, even with sunshine. For areas north of Interstate 64, we've seen ...

Cape Girardeau Public Schools announced the promotion of Dr. Brock Crowley to Assistant Superintendent of Support Services.

Hunters in Illinois harvested a preliminary total of 51,409 deer during the first weekend of the Illinois firearm deer season ...

It’s time to brace ourselves for a significant shift in our weather pattern here in Southern Illinois and surrounding areas.

Deputies from the Williamson County Sheriff's Office responded to a report of a stabbing on November 24 after 11 p.m.

A boil water order has been issued for several areas due to a water line break, according to De Soto Superintendent of Public ...

Thanksgiving is just two days away, and volunteers at the Newman Catholic Student Center in Carbondale are busy preparing for ...

The Carbondale Cycle Shop, a family-owned business since 1971, is now in its 54th year and operated by the second generation.

The City of Cape Girardeau Regional Airport is set to host a ribbon-cutting ceremony for its new flight service to ...

The City of Carbondale is advising residents about illegal materials that should not be flushed or poured down drains. These ...

Cairo is making history, quite literally, with the launch of the Cairo African American Heritage Trail & Oral History Project ...