A review in Fluids and Barriers of the CNS links mitochondrial dysfunction to blood-brain barrier failure and explores ...

The cells that line the blood vessels in our brains are highly selective. By deciding which molecules are allowed in and out of our most important organ, the barrier these cells form is critical for ...

Researchers at Sunnybrook Research Institute and the University of Toronto, led by Isabelle Aubert, Ph.D., have published results of a preclinical study examining focused ultrasound's potential to ...

In a recent primer paper published in the journal Current Biology, researchers elucidated the structure and function of the blood-brain barrier (BBB). It highlights the BBB as a complex, dynamic ...

Scientists have spent decades trying to get medicine across the blood-brain barrier. Two treatments for a rare genetic ...

A study recently published in Nature has identified a key factor in the age-related breakdown of the blood-brain barrier (BBB) and has demonstrated that this damage may be reversible, potentially ...

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

A rat study reveals that fetal growth restriction from gestational protein deficiency impairs blood-brain and blood-CSF ...

Series: "Delirium and Brain Aging" #5Key Points of This ArticleCerebrovascular aging begins with the loss of elasticity in ...

“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...