Our college football Week 11 picks for UofL vs Cal, UK vs Florida, Wake Forest vs Virginia, FSU vs Clemson and Indiana vs Penn State.

A UPS cargo plane crashed Tuesday at an airport in Louisville, Kentucky, where the company operates its largest package ...

LOUISVILLE, Ky. (WDRB) -- A teenager is in critical condition after a shooting in the Auburndale neighborhood just after ...

The Louisville football program came in at No. 14 in the most recent Associated Press Top 25 Poll and No. 15 in the most ...

Two Massachusetts men were arrested Tuesday in connection with a weekend explosion at Harvard Medical School, authorities ...

A UPS cargo plane crashed at a Louisville, Kentucky, airport where the company operates its largest package delivery hub. UPS ...

Police are responding to reports of a plane crash near Louisville International Airport in Kentucky on Tuesday.

Two male suspects were arrested Tuesday morning for allegedly setting off an explosive device inside a Harvard Medical School ...

The ACC Conference Championship race was turned on its ear in Week 10, with Miami and Georgia Tech taking unexpected losses. Douglas Farmer tells you why Louisville has the inside track to the ...

Now the Future Healers program has expanded to Bardstown Elementary School. It will bring hands-on health education to 230 elementary school students.

Gov. Andy Beshear was on hand in Bardstown to recognize and honor the Future Healers Bardstown Expansion. The ongoing ...

LOUISVILLE, Ky. — University of Louisville medical students got a boost to help start a new student-led clinic. SOS ...