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Cancer-associated fibroblasts play key roles in the pancreatic tumor microenvironment, but their targeting has yet been ...

Background Atrial fibrillation (AF) is linked to significant morbidity and mortality, with ischaemic stroke being a leading ...

Background Tobacco price is an important determinant of smoking behaviour. Using electronic point-of-sales (EPOS) data, this study assesses purchase price of factory-made cigarettes (FMC) and ...

Objective To characterise the use of the prostate specific antigen (PSA) test in primary care in England. Design Population based open cohort study. Setting England. Participants 10 235 805 male ...

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This cover highlights the article Programmed cell revival from imminent cell death enhances tissue repair and regeneration by ...

Key points A 39-year-old otherwise healthy man presented to the emergency department with severe rectal pain and a 3-day history of constipation. He had presented to another community emergency ...

How to free up time for meaningful work by Leslie A. Perlow, Constance Noonan Hadley and Eunice Eun Poking fun at meetings is the stuff of Dilbert cartoons—we can all joke about how soul-sucking and ...

Objective Certain leading medical organisations are considering alternatives to the Body Mass Index (BMI) as a predictor of the risk for non-communicable chronic disease (NCD) or death. Our objective ...

Introduction Only symptomatic treatments are available for patients with Parkinson’s disease (PD), the second most common chronic neurodegenerative disease worldwide, and it is therefore imperative to ...

Extreme heat impacts on child health and well-being due to immature thermoregulation, less sweating and a high surface-to-body mass ratio that make them more vulnerable to heat-related illness. Severe ...