We played a major role in revealing the biochemical steps of the RAS-RAF-MAP kinase pathway. We identified one of the major ...
Neuroblastoma RAS viral oncogene homolog (NRAS)-mutant melanoma is an aggressive form of skin cancer that develops because of ...
Research and development (R&D) expenses: R&D expenses were $35.1 million for the third quarter of 2025 compared to $17.9 million for the third quarter of 2024. The increase in expenses was primarily ...
Session Date/Time : Friday, December 12, from 12:30 p.m. – 2:00 p.m. CT ...
We played a major role in characterising the BRAF gene and its role in cancer, increasing our understanding of malignant melanoma.
A live webcast of the presentation will be accessible on the “ Events ” page of the BBOT website at A replay of the webcast will be available for at least 90 days following the event. About BBOT BBOT ...
A copy of the poster titled “BBO-11818: an orally bioavailable, highly potent and selective noncovalent pan-KRAS (ON) and (OFF) inhibitor with robust anti-tumor activity in KRAS-mutant preclinical ...
Experiments with genetically engineered mice suggest that breaking up the protein partnership could be an effective strategy.
Early-stage lung adenocarcinoma alters DNA methylation, mRNA transcription, and protein expression in adjacent tissues, exhibiting either steep changes at the tumor boundaries or shallow changes ...
T-cell acute lymphoblastic leukemia was reported in 1 patient 4.7 years after treatment and was determined to be directly related to the treatment 12; the patient’s blast cells had a single ...
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