A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Many medications and other therapeutic agents, including antibiotics and cancer therapies, must enter cells to reach their ...

A new machine learning method has achieved what even AlphaFold cannot — the design of intrinsically disordered proteins (IDPs), the shape-shifting biomolecules that make up nearly 30% of all human ...

PagePeek introduces an AI-powered paper evaluation system for rhodopsin research, integrating structural, spectroscopic, and ...

Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...

This valuable study identifies a brown adipose tissue-specific heat shock factor 1-alcohol dehydrogenase 5 (ADH5) molecular cascade as a regulator of systemic aging, showing that ADH5 deficiency ...

In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins ...

The novel computer method to encode synthetic protein sequences within cell lipid environments offers insights into how ...

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint the exact areas of the body ...

Background： Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and ...

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key ...

The dorsal vagal complex is a highly intricate structure composed of distinct transcriptional classes of glial and neuronal cells, exhibiting many similarities but also notable differences between ...