There are six keys to the Tennessee Titans getting a win over the San Francisco 49ers in Week 15.

The San Francisco 49ers have received some very concerning news regarding superstar running back Christian McCaffrey.

With a wide-open NFL this year, the 49ers have an opportunity to enter the playoffs hot and make a run.

Hall of Fame linebacker Patrick Willis is not only promoting Super Bowl LX and its fan-oriented events but he’s kept a close eye on the 49ers’ potential path there.

SANTA CLARA, Calif. (AP) — The San Francisco 49ers placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return from a knee injury this season. The move comes after ...

This Sunday will be no different as the Tennessee Titans travel to face the San Francisco 49ers. Five former 49ers will be in ...

The 49ers elevated two players from the practice squad to bolster the team’s defense heading into Sunday’s game against the ...