The common analogy of drug action is that of a lock and key, with a drug acting as a selective 'key' that fits into the 'lock' of a specific drug target. Over the past two decades, the concept of ...

GPCRs help cells sense and respond to their environment, with G proteins and β-arrestins serving as critical signaling effectors. Here, authors show that G proteins can directly bind β-arrestins and ...

Certain antibiotics are overused in most countries, while too few people receive the specific antibiotic treatments they need, according to a study of antibiotic use across 186 countries published in ...

Specific recommendations for prevention strategies often depend on the ischemic stroke/transient ischemic attack subtype. Therefore, new in this guideline is a section describing recommendations for ...