Synthetic human chromosomes may transform gene therapy by carrying large therapeutic genes without altering natural DNA. Here ...

Computational Biology and Bioinformatics (CBB), Biology, Biomedical Engineering (BME), Biostatistics and Bioinformatics, Center for Advanced Genomic Technologies, Duke Center for Genomic and ...

ABSTRACT: Based on the number of available sites for adenine, guanine, thymine, and cytosine on all DNA strands, the information theoretical entropy as well as the configurational entropy of a DNA ...

Scientists have finally uncovered the exact DNA sequence where human chromosomes fuse to form Robertsonian chromosomes, a mystery that has puzzled researchers for over a century. Using advanced genome ...

KANSAS CITY, Mo. — Kansas City scientists have made a “landmark” discovery that offers new insight into some cases of infertility, miscarriage and Down syndrome. A team of scientists at the Stowers ...

Kansas City, MO—September 24, 2025—Open a high school biology textbook, and you’ll see human chromosomes lined up two by two, like socks in a drawer. But in about one out of every 800 people, two ...

WHEN THE first draft of the DNA sequence that makes up the human genome was unveiled in 2000, America’s president at the time, Bill Clinton, announced that humankind was “learning the language with ...

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances ...

In a laboratory model of Down Syndrome, the CIRSPR gene editing technique successfully removed the duplicate chromosome that causes the condition while also augmenting cell function and fitness, and ...

The heart is a highly sex-biased organ, as sex shapes innumerable aspects of heart health and disease. Sex chromosomes and sex hormones —testosterone, progesterone, and estrogen— establish and ...

Researchers at Linköping University in Sweden made an unexpected discovery while investigating genetically unique women. Their insights advance our understanding of our most enigmatic chromosome, the ...