Background The peptide GPR15L is produced by colonic epithelial cells and has been implicated in T cell recruitment to the large intestine. However, its role in chronic colitis has been unclear so far ...
Research into GLP-1 medications and IBD is still at an early stage, and gastroenterologists aren't recommending that they be used outside their FDA-approved indications such as obesity and type 2 ...
New Clinical and Translational Data Presented at Major Medical Meetings Further Confirms the Disease-Modifying Potential of Nebokitug in Primary ...
Despite an expanding therapeutic armamentarium, remission rates in inflammatory bowel disease (IBD) appear to plateau at 30–50% after 1 year of treatment, leading to the concept of a therapeutic ...
Data highlight both SER-603’s rational design that targets microbial functions linked to mucosal healing and gastrointestinal inflammation in IBD, as well as the advancement of microbiome-based ...
STOCKHOLM — Severe infections requiring hospital treatment were associated with amore than threefold increase in risk for inflammatory bowel disease (IBD) in a prospective cohort study that used data ...
Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Establishing whether ...
CAMP is a vital antimicrobial peptide that plays a protective role in immune regulation New research is investigating how citrullination of cathelicidin (CAMP), mediated by peptidyl arginine deiminase ...
Please provide your email address to receive an email when new articles are posted on . TL1A inhibitors have shown both anti-inflammatory and anti-fibrotic activity in IBD. This class of drugs offers ...
The OMass partnership will boost Roche’s strategy in inflammatory bowel diseases, currently led by afimkibart, an anti-TL1A therapy the pharma obtained from its $7.1 billion acquisition of Telavant in ...
ABSTRACT: Background and Objectives: The gut-skin axis is a critical pathway linking gut microbiota composition and skin health. Evidence suggests that dysbiosis in inflammatory bowel disease (IBD) ...
ABSTRACT: Introduction: Ulcerative colitis (UC) falls under the spectrum of inflammatory bowel disease, presents with bloody diarrhea and abdominal pain, and is diagnosed endoscopically with erosive ...
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